MON-201 ER Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS

PCOS is associated with hyperandrogenism and growth arrest of antral follicles. Excess androgens work as a stage-specific inhibitor of a follicular growth suppressing the growth of late-stage follicles. Previously, we found that endoplasmic reticulum (ER) stress is activated in granulosa cells of an...

Descripción completa

Detalles Bibliográficos
Autores principales: Azhary, Jerilee, Harada, Miyuki, Takahashi, Nozomi, Hiraike, Osamu Wada, Fujii, Tomoyuki, Osuga, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Reproductive Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550975/
http://dx.doi.org/10.1210/js.2019-MON-201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550975/
http://dx.doi.org/10.1210/js.2019-MON-201

Ejemplares similares