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MON-201 ER Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS

PCOS is associated with hyperandrogenism and growth arrest of antral follicles. Excess androgens work as a stage-specific inhibitor of a follicular growth suppressing the growth of late-stage follicles. Previously, we found that endoplasmic reticulum (ER) stress is activated in granulosa cells of an...

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Detalles Bibliográficos
Autores principales:	Azhary, Jerilee, Harada, Miyuki, Takahashi, Nozomi, Hiraike, Osamu Wada, Fujii, Tomoyuki, Osuga, Yutaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Reproductive Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550975/ http://dx.doi.org/10.1210/js.2019-MON-201

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