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MON-217 Maternal Androgen Excess and Obesity Induce Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Offspring

Polycystic ovary syndrome (PCOS) is suggested to increase the risk for cardiovascular disease and type 2 diabetes. We hypothesized here that prenatal exposure to dihydrotestosterone (DHT) and/or maternal obesity lead to adverse metabolic and cardiac programming in the female offspring. The maternal...

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Detalles Bibliográficos
Autores principales: Manti, Maria, Fornes, Romina, Pironti, Gianluigi, McCann Haworth, Sarah, Zhuge, Zhengbing, Lindén Hirschberg, Angelica, De Castro Barbosa, Thais, Benrick, Anna, Carlström, Mattias, Andersson, Daniel, Stener-Victorin, Elisabet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551113/
http://dx.doi.org/10.1210/js.2019-MON-217