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MON-474 Dipeptidyl Peptidase-4 (DPP4) Inhibition Decreases Visceral Fat and Improves Glucose Metabolism in Overweight Women with Polycystic Ovarian Syndrome

Background: Women with PCOS have decreased GH secretion.(1) Diminished GH is associated with increased visceral adiposity and impaired vascular function. GH releasing hormone is the primary stimulus for GH secretion and a substrate of dipeptidyl peptidase-4 (DPP4).(2) We tested the hypothesis that o...

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Detalles Bibliográficos
Autores principales: Devin, Jessica, Nian, Hui, Wright, Patricia, Brown, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551164/
http://dx.doi.org/10.1210/js.2019-MON-474