Cargando…
Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats
BACKGROUND: We are investigating a double transgenic rat (dTGR) model, in which rats transgenic for the human angiotensinogen and renin genes are crossed. These rats develop moderately severe hypertension but die of end-organ cardiac and renal damage by week 7. The heart shows necrosis and fibrosis,...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC65512/ https://www.ncbi.nlm.nih.gov/pubmed/11835691 http://dx.doi.org/10.1186/1471-2261-2-3 |