Cargando…

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

The mouse X-inactivation center (Xic) locus represents a powerful model for understanding the links between genome architecture and gene regulation, with the non-coding genes Xist and Tsix showing opposite developmental expression patterns while being organized as an overlapping sense/antisense unit...

Descripción completa

Detalles Bibliográficos
Autores principales: van Bemmel, Joke G., Galupa, Rafael, Gard, Chris, Servant, Nicolas, Picard, Christel, Davies, James, Szempruch, Anthony James, Zhan, Yinxiu, Żylicz, Jan J., Nora, Elphège P., Lameiras, Sonia, de Wit, Elzo, Gentien, David, Baulande, Sylvain, Giorgetti, Luca, Guttman, Mitchell, Hughes, Jim R., Higgs, Douglas R., Gribnau, Joost, Heard, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551226/
https://www.ncbi.nlm.nih.gov/pubmed/31133748
http://dx.doi.org/10.1038/s41588-019-0412-0