Quadriceps miR-542-3p and -5p are elevated in COPD and reduce function by inhibiting ribosomal and protein synthesis

Reduced physical performance reduces quality of life in patients with chronic obstructive pulmonary disease (COPD). Impaired physical performance is, in part, a consequence of reduced muscle mass and function, which is accompanied by mitochondrial dysfunction. We recently showed that miR-542-3p and...

Descripción completa

Detalles Bibliográficos
Autores principales: Farre-Garros, Roser, Lee, Jen Y., Natanek, S. Amanda, Connolly, Martin, Sayer, Avan A., Patel, Harnish, Cooper, Cyrus, Polkey, Michael I., Kemp, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551227/
https://www.ncbi.nlm.nih.gov/pubmed/30676868
http://dx.doi.org/10.1152/japplphysiol.00882.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551227/
https://www.ncbi.nlm.nih.gov/pubmed/30676868
http://dx.doi.org/10.1152/japplphysiol.00882.2018

Ejemplares similares