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Attenuating dependence on structural data in computing protein energy landscapes

BACKGROUND: Nearly all cellular processes involve proteins structurally rearranging to accommodate molecular partners. The energy landscape underscores the inherent nature of proteins as dynamic molecules interconverting between structures with varying energies. In principle, reconstructing a protei...

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Detalles Bibliográficos
Autores principales: Morris, David, Maximova, Tatiana, Plaku, Erion, Shehu, Amarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551245/
https://www.ncbi.nlm.nih.gov/pubmed/31167640
http://dx.doi.org/10.1186/s12859-019-2822-5