MKL1 mediates TNF-α induced pro-inflammatory transcription by bridging the crosstalk between BRG1 and WDR5

Tumor necrosis factor alpha (TNF-α) is a cytokine that can potently stimulate the synthesis of a range of pro-inflammatory mediators in macrophages. The underlying epigenetic mechanism, however, is underexplored. Here we report that the transcriptional modulator megakaryocytic leukemia 1 (MKL1) is a...

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Detalles Bibliográficos
Autores principales: Xu, Wenping, Zhao, Quanyi, Wu, Min, Fang, Mingming, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551423/
https://www.ncbi.nlm.nih.gov/pubmed/29109331
http://dx.doi.org/10.7555/JBR.32.20170025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551423/
https://www.ncbi.nlm.nih.gov/pubmed/29109331
http://dx.doi.org/10.7555/JBR.32.20170025

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