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Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells()

Chromosomal aneuploidy is a defining feature of epithelial cancers. The pattern of aneuploidies is cancer-type specific. For instance, the gain of chromosome 13 occurs almost exclusively in colorectal cancer. We used microcell-mediated chromosome transfer to generate gains of chromosome 13 in the di...

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Detalles Bibliográficos
Autores principales: Wangsa, Darawalee, Braun, Rüdiger, Stuelten, Christina H., Brown, Markus, Bauer, Kerry M., Emons, Georg, Weston, Leigh A., Hu, Yue, Yang, Howard H., Vila-Casadesús, Maria, Lee, Maxwell P., Brauer, Philip, Warner, Lidia, Upender, Madhvi, Hummon, Amanda B., Camps, Jordi, Ried, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551473/
https://www.ncbi.nlm.nih.gov/pubmed/31174021
http://dx.doi.org/10.1016/j.neo.2019.04.009