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Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs

Viral suppressors of RNA silencing (VSRSs) are a diverse group of viral proteins that have evolved to disrupt eukaryotic RNA silencing pathways, thereby contributing to viral pathogenicity. The p19 protein is a VSRS that selectively binds to short interfering RNAs (siRNAs) over microRNAs (miRNAs). M...

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Detalles Bibliográficos
Autores principales: Foss, Dana V., Schirle, Nicole T., MacRae, Ian J., Pezacki, John Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551489/
https://www.ncbi.nlm.nih.gov/pubmed/31021526
http://dx.doi.org/10.1002/2211-5463.12644