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Specific zinc finger‐induced methylation of PD‐L1 promoter inhibits its expression

DNA methylation of promoter regions is often associated with epigenetic silencing of gene expression, and DNA methyltransferase (DNMTs) has been used to suppress gene expression. In order to explore the synergistic roles of two methyltransferase members Dnmt3a and Dnmt1, we constructed expression pl...

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Detalles Bibliográficos
Autores principales: Li, Xue, Wang, Zhenni, Huang, Jiansheng, Luo, Huazao, Zhu, Sibo, Yi, Han, Zheng, Liuhai, Hu, Bo, Yu, Lili, Li, Lingzhi, Xie, Jun, Zhu, Naishuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551500/
https://www.ncbi.nlm.nih.gov/pubmed/31090214
http://dx.doi.org/10.1002/2211-5463.12568