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Assessment of microRNA expression in leukemic cells as predictors of sensitivity to purine nucleoside analogs, fludarabine and cladribine, in chronic lymphocytic leukemia patients

Background: Great progress has been achieved lately in the therapy for chronic lymphocytic leukemia (CLL), one of the most frequently diagnosed adult leukemias. New classes of drugs, such as kinase inhibitors and BCL-2 protein antagonists, have been approved for treatment of CLL patients. Despite th...

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Detalles Bibliográficos
Autores principales: Szymczyk, Agnieszka, Chocholska, Sylwia, Macheta, Arkadiusz, Szczepanek, Dariusz, Hus, Marek, Podhorecka, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551592/
https://www.ncbi.nlm.nih.gov/pubmed/31239767
http://dx.doi.org/10.2147/CMAR.S191311