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Full antagonist of the IL-7 receptor suppresses chronic inflammation in non-human primate models by controlling antigen-specific memory T cells

Targeting the expansion of pathogenic memory immune cells is a promising therapeutic strategy to prevent chronic autoimmune attacks. Interleukin 7 (IL-7) is a limiting and potent cytokine produced by epithelial and stromal cells sustaining T-lymphocytes development, homeostasis and cell metabolism....

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Detalles Bibliográficos
Autores principales: Belarif, Lyssia, Vanhove, Bernard, Poirier, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551675/
https://www.ncbi.nlm.nih.gov/pubmed/31225460
http://dx.doi.org/10.15698/cst2018.12.168