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The NLRC4 inflammasome requires IRF8-dependent production of NAIPs
Activation of the NLRC4 inflammasome is crucial for defense against bacterial species that have flagellin or the type III secretion system (T3SS). We have discovered the role of interferon regulatory factor 8 (IRF8) in mediating NLRC4 inflammasome activation. IRF8 is required for the transcription o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Shared Science Publishers OG
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551684/ https://www.ncbi.nlm.nih.gov/pubmed/31225480 http://dx.doi.org/10.15698/cst2018.06.141 |