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SAT-163 Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets

Pancreatic β-cells undergo profound hyperplasia during pregnancy to maintain maternal euglycemia. Failure to reprogram β-cells into a more replicative state has been found to underlie susceptibility to gestational diabetes (GDM). Our laboratory has recently identified a requirement for prolactin rec...

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Detalles Bibliográficos
Autores principales: Pepin, Mark, Wende, Adam, Banerjee, Ronadip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551691/
http://dx.doi.org/10.1210/js.2019-SAT-163