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Putting together and taking apart: assembly and disassembly of the Rad51 nucleoprotein filament in DNA repair and genome stability

Homologous recombination is a key mechanism providing both genome stability and genetic diversity in all living organisms. Recombinases play a central role in this pathway: multiple protein subunits of Rad51 or its orthologues bind single-stranded DNA to form a nucleoprotein filament which is essent...

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Detalles Bibliográficos
Autores principales: Andriuskevicius, Tadas, Kotenko, Oleksii, Makovets, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551702/
https://www.ncbi.nlm.nih.gov/pubmed/31225474
http://dx.doi.org/10.15698/cst2018.05.134