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Exosomal secretion of truncated cytosolic lysyl-tRNA synthetase induces inflammation during cell starvation

Previous work by Kim, et al. (2017) unveiled that lysyl-tRNA synthetase (KRS) is secreted through a mechanism involving syntenin-containing exosomes. They described how KRS, commonly known as part of the translational machinery in the cytoplasm, is secreted into the extracellular space where it indu...

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Detalles Bibliográficos
Autores principales: Kim, Sang Bum, Cho, Seongmin, Kim, Sunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551704/
https://www.ncbi.nlm.nih.gov/pubmed/31225477
http://dx.doi.org/10.15698/cst2018.05.137