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R-loops: formation, function, and relevance to cell stress
Exposure of genomic, single-stranded DNA (ssDNA) during transcription and replication creates opportunities for the formation of inappropriate secondary structures. Cells manage this exposure by using topoisomerases and helicases to reduce the inherent topological stress that arises from unwinding t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Shared Science Publishers OG
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551709/ https://www.ncbi.nlm.nih.gov/pubmed/31225499 http://dx.doi.org/10.15698/cst2019.02.175 |