SAT-327 Targeting FOXA1-mediated Repression of TGF-B Signaling Supresses Castration-Resistant Prostate Cancer Progression

Prostate cancer (PCa) progressed to castration resistance (CRPC) is a fatal disease. CRPC tumors develop resistance to new-generation anti-androgen enzalutamide through lineage plasticity, characterized by epithelial-mesenchymal transition (EMT) and basal-like phenotype. FOXA1 is a transcription fac...

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Detalles Bibliográficos
Autor principal: Park, Su Hong (Kevin)
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551725/
http://dx.doi.org/10.1210/js.2019-SAT-327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551725/
http://dx.doi.org/10.1210/js.2019-SAT-327

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