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SAT-327 Targeting FOXA1-mediated Repression of TGF-B Signaling Supresses Castration-Resistant Prostate Cancer Progression
Prostate cancer (PCa) progressed to castration resistance (CRPC) is a fatal disease. CRPC tumors develop resistance to new-generation anti-androgen enzalutamide through lineage plasticity, characterized by epithelial-mesenchymal transition (EMT) and basal-like phenotype. FOXA1 is a transcription fac...
Autor principal: | Park, Su Hong (Kevin) |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551725/ http://dx.doi.org/10.1210/js.2019-SAT-327 |
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