Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions

Ageing and age-related diseases are characterised by increased oxidative and proteotoxic stress, which results in negative effects on cell function and survival. The cell possesses several mechanisms to deal with damaged proteins, including degradation via macroautophagy (hereafter called autophagy)...

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Detalles Bibliográficos
Autores principales: Otten, Elsje G., Stefanatos, Rhoda, Carroll, Bernadette, Korolchuk, Viktor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Microreview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551744/
https://www.ncbi.nlm.nih.gov/pubmed/31225472
http://dx.doi.org/10.15698/cst2018.04.132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551744/
https://www.ncbi.nlm.nih.gov/pubmed/31225472
http://dx.doi.org/10.15698/cst2018.04.132

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