Cargando…

SAT-032 In Vitro Characterization Of GPR101 Transcriptional Regulation

Background: X-linked acrogigantism (X-LAG) is a novel syndrome of early childhood-onset gigantism caused by duplications of GPR101, a gene that is strongly upregulated in the pituitary adenomas (PAs) of the patients. Aim: To study the human GPR101 promoter. Methods:GPR101 promoter annotation was car...

Descripción completa

Detalles Bibliográficos
Autores principales: Trivellin, Giampaolo, Stigliano, Antonio, Wu, TJ, Stratakis, Constantine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551756/
http://dx.doi.org/10.1210/js.2019-SAT-032