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SAT-024 Adipose Specific Inactivation of Aromatase is Sufficient to Cause Adiposity and Impaired Glucose Tolerance in Mice

Aromatase synthesizes estrogens from androgens. While the gonads are major sites of aromatase expression, it is expressed in multiple other organs including adipose tissue, brain and bone. In global aromatase knockouts in mice, studied by us, or man aromatase deficiency there are phenotypes of adipo...

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Detalles Bibliográficos
Autores principales: Oz, Orhan, Lo, Su-Tang, Azimaie, Taha, Ye, Risheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551796/
http://dx.doi.org/10.1210/js.2019-SAT-024