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Attenuating MKRN1 E3 ligase-mediated AMPKα suppression increases tolerance against metabolic stresses in mice

The 5' adenosine monophosphate-activated protein kinase (AMPK) is an essential energy sensor in the cell, which, at low energy levels, instigates the cellular energy-generating systems along with suppression of the anabolic signaling pathways. The activation of AMPK through phosphorylation is a...

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Detalles Bibliográficos
Autores principales: Han, Hyunji, Chae, Sehyun, Hwang, Daehee, Song, Jaewhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551801/
https://www.ncbi.nlm.nih.gov/pubmed/31225456
http://dx.doi.org/10.15698/cst2018.11.164