Constitutional Mosaic Epimutations - a hidden cause of cancer?

Silencing of tumor suppressor genes by promoter hypermethylation is a key mechanism to facilitate cancer progression in many malignancies. While promoter hypermethylation can occur at later stages of the carcinogenesis process, constitutional methylation of key tumor suppressors may be an initiating...

Descripción completa

Detalles Bibliográficos
Autores principales: Lønning, Per E., Eikesdal, Hans P., Løes, Inger M., Knappskog, Stian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551830/
https://www.ncbi.nlm.nih.gov/pubmed/31225507
http://dx.doi.org/10.15698/cst2019.04.183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551830/
https://www.ncbi.nlm.nih.gov/pubmed/31225507
http://dx.doi.org/10.15698/cst2019.04.183

Ejemplares similares