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Therapeutic potential of HDAC6 in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease in adults and no effective treatments exist. Mutations in FUS are one of the genetic causes of familial ALS. We used induced pluripotent stem cells (iPSCs) derived from FUS-ALS patients to investigate the pathological...

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Detalles Bibliográficos
Autores principales: Guo, Wenting, Van Den Bosch, Ludo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551843/
https://www.ncbi.nlm.nih.gov/pubmed/31225447
http://dx.doi.org/10.15698/cst2018.01.120