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Therapeutic potential of HDAC6 in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease in adults and no effective treatments exist. Mutations in FUS are one of the genetic causes of familial ALS. We used induced pluripotent stem cells (iPSCs) derived from FUS-ALS patients to investigate the pathological...
Autores principales: | Guo, Wenting, Van Den Bosch, Ludo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551843/ https://www.ncbi.nlm.nih.gov/pubmed/31225447 http://dx.doi.org/10.15698/cst2018.01.120 |
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