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SAT-153 Role Of Increased Serum- And Glucocorticoid-inducible Kinase 1 (SGK1) Activity In Gluconeogenesis And Liver Metabolism During Metabolic Syndrome.
SGK1 is a serine/threonine kinase expressed in different tissues included liver. At the cellular level, SGK1 expression is upregulated by multiple stimuli including gluco- and mineralo-corticoids, glucose and growth factors. Its activation depends on the PI3K pathway, playing a role in insulin sensi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551854/ http://dx.doi.org/10.1210/js.2019-SAT-153 |