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SAT-153 Role Of Increased Serum- And Glucocorticoid-inducible Kinase 1 (SGK1) Activity In Gluconeogenesis And Liver Metabolism During Metabolic Syndrome.

SGK1 is a serine/threonine kinase expressed in different tissues included liver. At the cellular level, SGK1 expression is upregulated by multiple stimuli including gluco- and mineralo-corticoids, glucose and growth factors. Its activation depends on the PI3K pathway, playing a role in insulin sensi...

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Detalles Bibliográficos
Autores principales: Velazquez-Garcia, Silvia, Vastola, Arianna, Sierra-Ramos, Catalina, Hernandez, Guadalberto, Alvarez de la Rosa, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551854/
http://dx.doi.org/10.1210/js.2019-SAT-153