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Phorbol esters and CAMP differentially regulate the expression of CD4 and CD8 in human thymocytes
BACKGROUND: Intrathymic development and selection of the T lymphocyte repertoire is restricted by the interactions of the T cell antigen receptor and CD4 or CD8 co-receptors with self major histocompatibility complex molecules. Positive or negative selection depends on a tight regulatory control of...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC65519/ https://www.ncbi.nlm.nih.gov/pubmed/11835689 http://dx.doi.org/10.1186/1471-2172-3-1 |