SAT-161 Macrophage Alterations in Islets of Obese Mice Linked to Beta Cell Compensation or Beta Cell Dedifferentiation in Diabetes

Background: Pancreatic beta cell dedifferentiation may be an important contributing factor to beta cell failure in type 2 diabetes, but the triggering stimuli are poorly understood. Macrophage levels are elevated in the islets of humans and mice with type 2 diabetes, but their effect on beta cell id...

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Detalles Bibliográficos
Autores principales: Chan, Jeng Yie, Lee, Kailun, Maxwell, Emma, Liang, Cassandra, Laybutt, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551978/
http://dx.doi.org/10.1210/js.2019-SAT-161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551978/
http://dx.doi.org/10.1210/js.2019-SAT-161

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