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SAT-161 Macrophage Alterations in Islets of Obese Mice Linked to Beta Cell Compensation or Beta Cell Dedifferentiation in Diabetes

Background: Pancreatic beta cell dedifferentiation may be an important contributing factor to beta cell failure in type 2 diabetes, but the triggering stimuli are poorly understood. Macrophage levels are elevated in the islets of humans and mice with type 2 diabetes, but their effect on beta cell id...

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Detalles Bibliográficos
Autores principales:	Chan, Jeng Yie, Lee, Kailun, Maxwell, Emma, Liang, Cassandra, Laybutt, Ross
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Diabetes Mellitus and Glucose Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551978/ http://dx.doi.org/10.1210/js.2019-SAT-161

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