SAT-462 AIP Mutation-Positive Patients with Somatotropinomas End up Taller and Requiring Radiotherapy More Often Compared to AIP Mutation-Negative Patients: Data from 784 Familial and Young-Onset Cases

Introduction: Germline mutations in the aryl hydrocarbon receptor-interacting protein gene (AIP) are responsible for up to 50% of familial isolated pituitary adenoma (FIPA) kindreds affected only with somatotropinomas. AIP mutation-positive (AIPmut) somatotropinomas present earlier, more aggressivel...

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Detalles Bibliográficos
Autores principales: Marques, Pedro, Caimari, Francisca, Hernández-Ramírez, Laura, Collier, David, Grossman, Ashley, Korbonits, Márta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552023/
http://dx.doi.org/10.1210/js.2019-SAT-462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552023/
http://dx.doi.org/10.1210/js.2019-SAT-462

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