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SAT-030 Role of PARP-1 in Regulating Cytokine-Mediated Pro-Inflammatory Transcriptional Responses in Macrophages

Macrophages (MF) are major components of the innate immune system involved in mounting inflammatory responses against infection or injury in the host. MF activated by microbial agents, cytokines, or interferon-gamma (IFNg) are highly effective at resolving infections. Mice lacking in the enzyme Poly...

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Detalles Bibliográficos
Autores principales: Gupte, Rebecca, Nandu, Tulip, Kraus, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552028/
http://dx.doi.org/10.1210/js.2019-SAT-030