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SAT-390 New Cortisol Threshold for Diagnosis of Adrenal Insufficiency After Cosyntropin Stimulation Testing Using the Elecsys Cortisol II, Access Cortisol, and LC-MS/MS Assays

The peak cortisol response 30 or 60 minutes after cosyntropin [ACTH (1-24)] is regarded to be ≥18 μg/dL (500 nmol/L). This threshold is based on older immunoassays using polyclonal antibodies to detect cortisol. The use of more specific monoclonal antibody immunoassays or LC-MS/MS has been reported...

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Detalles Bibliográficos
Autores principales: Javorsky, Bradley, Carroll, Ty, Algeciras-Schimnich, Alicia, Singh, Ravinder, Colon-Franco, Jessica, Findling, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552067/
http://dx.doi.org/10.1210/js.2019-SAT-390