SAT-151 Hyperinsulinemia-Driven Progressive Metabolic Dysfunction in Male Mice with Liver-Specific CEACAM1 Deletion

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin sensitivity by promoting hepatic insulin clearance. Mice with global null mutation (Cc1(-/-)) or with liver-specific inactivation (L-SACC1) of Ceacam1 gene display hyperinsulinemia due to impaired insulin clearance...

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Detalles Bibliográficos
Autores principales: Ghadieh, Hilda, Russo, Lucia, Muturi, Harrison, Ghanem, Simona, Manaserh, Iyad, Noh, Hye Lim, Suk, Sujin, Kim, Jason, Gatto-Weis, Cara, Hill, Jennifer, Najjar, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552123/
http://dx.doi.org/10.1210/js.2019-SAT-151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552123/
http://dx.doi.org/10.1210/js.2019-SAT-151

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