SAT-LB061 Sex-Specific Role of Retinoic Acid Receptor Alpha Signaling in Adrenal Cortex Development and Functional Zonation

Primary aldosteronism is the major cause of secondary arterial hypertension. Recurrent somatic mutations in KCNJ5, CACNA1D, ATP1A1 and ATP2B3 have been identified in aldosterone producing adenoma (APA). Although the role of these mutations in regulating aldosterone biosynthesis has been clearly esta...

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Detalles Bibliográficos
Autores principales: EL ZEIN, Rami, Soria, Audrey, Golib Dzib, Jose Felipe, Rickard, Amanda, Fernandes-Rosa, Fabio Luiz, Samson-Couterie, Benoit, Giscos-Douriez, Isabelle, Rocha, Angélique, Poglitsch, Marko, Gomez-Sanchez, Celso, Amar, Laurence, Ghyselinck, Norbert, Benecke, Arndt, Zennaro, Maria-Christina, Boulkroun, Sheerazed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552146/
http://dx.doi.org/10.1210/js.2019-SAT-LB061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552146/
http://dx.doi.org/10.1210/js.2019-SAT-LB061

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