SAT-353 The Synthetic Vitamin D Analog EB1089 Restricts Adrenocortical Tumor Proliferation in NCI-H295 Xenograft Model

The vitamin D (VD) receptor (VDR) is underexpressed in adult and pediatric adrenocortical tumors (ACT), especially in carcinomas (ACC). VDR activation by VD represses B-catenin signaling in different types of tumors that like ACT, present aberrant B-catenin expression. EB1089 is a potent synthetic V...

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Detalles Bibliográficos
Autores principales: Bueno, Ana, More, Candy, Ramalho, Fernando, Moreira, Ayrton, De Castro, Margaret, Rauber Antonini, Sonir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552194/
http://dx.doi.org/10.1210/js.2019-SAT-353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552194/
http://dx.doi.org/10.1210/js.2019-SAT-353

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