SAT-171 Effective Intrajejunal Wall Delivery of Recombinant Human Insulin via a Self-Deployed Ingestible Capsule in Anesthetized Swines: A Pharmacokinetic and Pharmacodynamic Study

BACKGROUND: Biotherapeutic agents must be administered parenterally to reach and maintain therapeutic blood concentrations, lowering patient compliance and complicating long-term care. We have developed an ingestible robotic pill capable of delivering a variety of drugs directly into the wall of the...

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Detalles Bibliográficos
Autores principales: Hashim, Mir, Korupolu, Radhika, Syed, Baber, Horlen, Kyle, Karamchedu, Padma, Beraki, Simret, Dhalla, Arvinder, Ruffy, Rodolphe, Imran, Mir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552267/
http://dx.doi.org/10.1210/js.2019-SAT-171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552267/
http://dx.doi.org/10.1210/js.2019-SAT-171

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