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SAT-171 Effective Intrajejunal Wall Delivery of Recombinant Human Insulin via a Self-Deployed Ingestible Capsule in Anesthetized Swines: A Pharmacokinetic and Pharmacodynamic Study
BACKGROUND: Biotherapeutic agents must be administered parenterally to reach and maintain therapeutic blood concentrations, lowering patient compliance and complicating long-term care. We have developed an ingestible robotic pill capable of delivering a variety of drugs directly into the wall of the...
Autores principales: | Hashim, Mir, Korupolu, Radhika, Syed, Baber, Horlen, Kyle, Karamchedu, Padma, Beraki, Simret, Dhalla, Arvinder, Ruffy, Rodolphe, Imran, Mir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552267/ http://dx.doi.org/10.1210/js.2019-SAT-171 |
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