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SAT-169 Selective Nonpeptide Somatostatin Subtype 5 (sst5) Agonists Suppress Glucose- and Sulfonylurea-Induced Insulin Secretion in Rats

Congenital hyperinsulinism (CHI) results from mutations within the insulin secretion pathway and is characterized by excessive and/or inappropriate insulin secretion by pancreatic islet β-cells. CHI is the most common cause of persistent hypoglycemia in newborns and infants and is estimated to affec...

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Detalles Bibliográficos
Autores principales: Sturchler, Emmanuel, Fowler, Melissa, Athanacio, Jon, Kredel, Taylor, Johns, Michael, Zhao, Jian, Wang, Shimiao, Luo, Rosa, Kusnetzow, Ana, Zhu, Yun Fei, Madan, Ajay, Struthers, Scott, Betz, Stephen, Markison, Stacy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552315/
http://dx.doi.org/10.1210/js.2019-SAT-169