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SAT-361 Rapid Glucocorticoid Regulation of Adrenoreceptor Trafficking Desensitizes CRH Neurons to Noradrenergic Activation

Stress activates the hypothalamic-pituitary-adrenal (HPA) axis via excitatory noradrenergic projections from the brainstem to corticotropin releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN). The resulting systemic release of glucocorticoids feeds back to the hypothala...

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Detalles Bibliográficos
Autores principales: Weiss, Grant, Tasker, Jeffrey, Neilsen, Alyssa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552463/
http://dx.doi.org/10.1210/js.2019-SAT-361