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SAT-557 Functional Thyrotropin Receptor Antibodies Confirm a Novel Graves' Disease Animal Model

Background / Objectives: A novel long-term animal model for human Graves’ disease (GD) was recently established in mice (Endocrinology 2015; 156: 1577-1589) using nine immunizations with recombinant adenovirus (Ad) expressing the extracellular A-subunit of the human thyrotropin receptor (TSHR) over...

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Detalles Bibliográficos
Autores principales: Diana, Tanja, Ungerer, Martin, Reimann, Andreas, Faßbender, Julia, Kanitz, Michael, Kahaly, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552466/
http://dx.doi.org/10.1210/js.2019-SAT-557