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Pharmacokinetics of artesunate after single oral administration to rats

BACKGROUND: Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and how this influences absorption. In order to study the absorption phase of the kinetics of artesunate...

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Detalles Bibliográficos
Autores principales: Olliaro, Piero L, Nair, Naren K, Sathasivam, Kathir, Mansor, Sharif M, Navaratnam, Vis
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC65525/
https://www.ncbi.nlm.nih.gov/pubmed/11835690
http://dx.doi.org/10.1186/1471-2210-1-12