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Pharmacokinetics of artesunate after single oral administration to rats
BACKGROUND: Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and how this influences absorption. In order to study the absorption phase of the kinetics of artesunate...
Autores principales: | Olliaro, Piero L, Nair, Naren K, Sathasivam, Kathir, Mansor, Sharif M, Navaratnam, Vis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC65525/ https://www.ncbi.nlm.nih.gov/pubmed/11835690 http://dx.doi.org/10.1186/1471-2210-1-12 |
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