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SAT-029 Understanding The Functions Of Parp-1 In Embryonic Stem Cells

Poly(ADP-ribose) polymerase 1 (PARP-1) is an abundant nuclear enzyme that plays diverse roles in a variety of nuclear processes, including DNA damage detection and repair, chromatin remodeling, transcriptional regulation, and RNA processing. PARP-1 functions both as an enzyme, through its NAD+-depen...

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Detalles Bibliográficos
Autores principales: Jones, Aarin, Kraus, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552501/
http://dx.doi.org/10.1210/js.2019-SAT-029