SAT-178 Parasitoid Wasp Venom Elevates Sorbitol and Alters Expression of Metabolic Genes in Human Kidney Cells

Venom from the parasitoid wasp Nasonia vitripennis dramatically elevates sorbitol levels in its natural fly hosts. In humans, sorbitol elevation is associated with complications of diabetes. Here we demonstrate that venom also induces this disease-relevant phenotype in human cells, and investigate p...

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Detalles Bibliográficos
Autores principales: Siebert, Aisha, Doucette, Luticha, Simpson-Haidaris, Patricia, Werren, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552522/
http://dx.doi.org/10.1210/js.2019-SAT-178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552522/
http://dx.doi.org/10.1210/js.2019-SAT-178

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