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SAT-559 Intranuclear Dynamics of RTHα Mutant Thyroid Hormone Receptors
Abstract: Resistance to Thyroid Hormone α (RTHα), a reduced sensitivity to thyroid hormone (T3) in peripheral tissues, is caused by mutations in thyroid hormone receptor α (TRα), a nuclear receptor that regulates gene expression when bound to T3. These mutations often result in receptors incapable o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552555/ http://dx.doi.org/10.1210/js.2019-SAT-559 |