SAT-LB035 The G Protein-Coupled Estrogen Receptor GPER Plays a Dominant Role in Human Islet Cell Proliferation upon High Glucose

Estrogen exerts its effects through genomic and rapid extra-nuclear signaling pathways. The classic estrogen receptors, ERα and ERβ have demonstrated favorable effects on beta-cell function and survival but their clinical utility has been questioned owing to oncogenic potential and concerns regardin...

Descripción completa

Detalles Bibliográficos
Autores principales: Shaklai, Sigal, Grafi-Cohen, Meital, Sharon, Orli, Shefer, Gabi, Somjen, Dalia, Stern, Naftali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Diabetes Mellitus and Glucose Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552641/
http://dx.doi.org/10.1210/js.2019-SAT-LB035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552641/
http://dx.doi.org/10.1210/js.2019-SAT-LB035

Ejemplares similares