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SAT-LB035 The G Protein-Coupled Estrogen Receptor GPER Plays a Dominant Role in Human Islet Cell Proliferation upon High Glucose

Estrogen exerts its effects through genomic and rapid extra-nuclear signaling pathways. The classic estrogen receptors, ERα and ERβ have demonstrated favorable effects on beta-cell function and survival but their clinical utility has been questioned owing to oncogenic potential and concerns regardin...

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Detalles Bibliográficos
Autores principales:	Shaklai, Sigal, Grafi-Cohen, Meital, Sharon, Orli, Shefer, Gabi, Somjen, Dalia, Stern, Naftali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Diabetes Mellitus and Glucose Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552641/ http://dx.doi.org/10.1210/js.2019-SAT-LB035

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